Evidence Based
The more you think about it, the weirder it gets.
Obviously we have reproductive differences but, beyond that, do women and men really vary that much?
Especially when it comes to science. We use rats to estimate how stuff affects us for crying out loud. We share about 50% of the same genes as fruit flies and some have argued that our societal structures are similar to that of lobsters.
When it comes to comparing one human against the other then 99.9% similarity may be an understatement because we don’t want to use more decimal places.
And yet, despite this, we find numerous claims that supplements can benefit women and men differently beyond sex-based anatomical differences.
To rub salt in the wound they are also all called vitamins for what I can only assume to be marketing or negligence. The amount of times I’ve seen calcium included in lists of vitamins for women’s health is equal parts staggering and saddening (we’ll get to why that’s wrong in a moment).
Screw “vitamin,” the most commonly misused term by far in this regard. Want to know vitamins for women? Folic acid prenatal vitamins, boom, done, that’s it.
It’s a useless question.
A much better one is this: “What supplements should I, as a woman, consider that men do not need to consider?”
And simple questions beget simple answers.
Lastly, if you want to support the show, please drop a quick review of it over on iTunes. It really helps!
Timestamps:
3:29 – Why are there supplements for women and what are the differences in these products?
10:00 – What supplements do you recommend for women?
Mentioned on The Show:
What did you think of this episode? Have anything else to share? Let me know in the comments below!
+ Scientific References
- Viswanathan, M., Treiman, K. A., Kish-Doto, J., Middleton, J. C., Coker-Schwimmer, E. J. L., & Nicholson, W. K. (2017). Folic acid supplementation for the prevention of neural tube defects an updated evidence report and systematic review for the US preventive services task force. In JAMA – Journal of the American Medical Association (Vol. 317, Issue 2, pp. 190–203). American Medical Association. https://doi.org/10.1001/jama.2016.19193
- Imhoff-Kunsch, B., Stein, A. D., Villalpando, S., Martorell, R., & Ramakrishnan, U. (2011). Docosahexaenoic acid supplementation from mid-pregnancy to parturition influenced breast milk fatty acid concentrations at 1 month postpartum in mexican women. Journal of Nutrition, 141(2), 321–326. https://doi.org/10.3945/jn.110.126870
- Ramakrishnan, U., Stinger, A., Digirolamo, A. M., Martorell, R., Neufeld, L. M., Rivera, J. A., Schnaas, L., Stein, A. D., & Wang, M. (2015). Prenatal docosahexaenoic acid supplementation and offspring development at 18 months: Randomized controlled trial. PLoS ONE, 10(8). https://doi.org/10.1371/journal.pone.0120065
- Hibbeln, J. R., Davis, J. M., Steer, C., Emmett, P., Rogers, I., Williams, C., & Golding, J. (2007). Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study. Lancet, 369(9561), 578–585. https://doi.org/10.1016/S0140-6736(07)60277-3
- Ramakrishnan, U., Gonzalez-Casanova, I., Schnaas, L., DiGirolamo, A., Quezada, A. D., Pallo, B. C., Hao, W., Neufeld, L. M., Rivera, J. A., Stein, A. D., & Martorell, R. (2016). Prenatal supplementation with DHA improves attention at 5 y of age: A randomized controlled trial. American Journal of Clinical Nutrition, 104(4), 1075–1082. https://doi.org/10.3945/ajcn.114.101071
- Calcium, I. of M. (US) C. to R. D. R. I. for V. D. and, Ross, A. C., Taylor, C. L., Yaktine, A. L., & Valle, H. B. Del. (2011). Overview of Calcium. https://www.ncbi.nlm.nih.gov/books/NBK56060/
- Gonzales, G. F., Córdova, A., Vega, K., Chung, A., Villena, A., Góñez, C., & Castillo, S. (2002). Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia, 34(6), 367–372. https://doi.org/10.1046/j.1439-0272.2002.00519.x
- Stone, M., Ibarra, A., Roller, M., Zangara, A., & Stevenson, E. (2009). A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen. Journal of Ethnopharmacology, 126(3), 574–576. https://doi.org/10.1016/j.jep.2009.09.012
- Zenico, T., Cicero, A. F. G., Valmorri, L., Mercuriali, M., & Bercovich, E. (2009). Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction: A randomised, double-blind clinical trial. Andrologia, 41(2), 95–99. https://doi.org/10.1111/j.1439-0272.2008.00892.x
- Dording, C. M., Fisher, L., Papakostas, G., Farabaugh, A., Sonawalla, S., Fava, M., & Mischoulon, D. (2008). A double-blind, randomized, pilot dose-finding study of maca root (L. Meyenii) for the management of SSRI-induced sexual dysfunction. CNS Neuroscience and Therapeutics, 14(3), 182–191. https://doi.org/10.1111/j.1755-5949.2008.00052.x
- Brooks, N. A., Wilcox, G., Walker, K. Z., Ashton, J. F., Cox, M. B., & Stojanovska, L. (2008). Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content. Menopause, 15(6), 1157–1162. https://doi.org/10.1097/gme.0b013e3181732953
- Tagliaferri, V., Romualdi, D., Immediata, V., De Cicco, S., Di Florio, C., Lanzone, A., & Guido, M. (2017). Metformin vs myoinositol: which is better in obese polycystic ovary syndrome patients? A randomized controlled crossover study. Clinical Endocrinology, 86(5), 725–730. https://doi.org/10.1111/cen.13304
- Fruzzetti, F., Perini, D., Russo, M., Bucci, F., & Gadducci, A. (2017). Comparison of two insulin sensitizers, metformin and myo-inositol, in women with polycystic ovary syndrome (PCOS). Gynecological Endocrinology, 33(1), 39–42. https://doi.org/10.1080/09513590.2016.1236078
- Minozzi, M., D’Andrea, G., & Unfer, V. (2008). Treatment of hirsutism with myo-inositol: A prospective clinical study. Reproductive BioMedicine Online, 17(4), 579–582. https://doi.org/10.1016/S1472-6483(10)60248-9
- Zacchè, M. M., Caputo, L., Filippis, S., Zacchè, G., Dindelli, M., & Ferrari, A. (2009). Efficacy of myo-inositol in the treatment of cutaneous disorders in young women with polycystic ovary syndrome. Gynecological Endocrinology, 25(8), 508–513. https://doi.org/10.1080/09513590903015544
- E Carmina. (n.d.). PCOS: metabolic impact and long-term management – PubMed. Retrieved April 29, 2021, from https://pubmed.ncbi.nlm.nih.gov/23232534/
- Genazzani, A. D., Prati, A., Santagni, S., Ricchieri, F., Chierchia, E., Rattighieri, E., Campedelli, A., Simoncini, T., & Artini, P. G. (2012). Differential insulin response to myo-inositol administration in obese polycystic ovary syndrome patients. Gynecological Endocrinology, 28(12), 969–973. https://doi.org/10.3109/09513590.2012.685205
- Maeba, R., Hara, H., Ishikawa, H., Hayashi, S., Yoshimura, N., Kusano, J., Takeoka, Y., Yasuda, D., Okazaki, T., Kinoshita, M., & Teramoto, T. (2008). Myo-inositol treatment increases serum plasmalogens and decreases small dense LDL, particularly in hyperlipidemic subjects with metabolic syndrome. Journal of Nutritional Science and Vitaminology, 54(3), 196–202. https://doi.org/10.3177/jnsv.54.196
- S Gerli, E Papaleo, A Ferrari, & G C Di Renzo. (n.d.). Randomized, double blind placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS – PubMed. Retrieved April 29, 2021, from https://pubmed.ncbi.nlm.nih.gov/18074942/
- Momoeda, M., Sasaki, H., Tagashira, E., Ogishima, M., Takano, Y., & Ochiai, K. (2014). Efficacy and safety of vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: A prospective, open-label study. Advances in Therapy, 31(3), 362–373. https://doi.org/10.1007/s12325-014-0106-z
- Medicines Agency, E. (2010). 7 Westferry Circus • Canary Wharf • London E14 4HB • United Kingdom. https://www.ema.europa.eu/en/documents/herbal-report/superseded-assessment-report-vitex-agnus-castus-l-fructus-first-version_en.pdf
- Schellenberg, R. (2001). Treatment for the premenstrual syndrome with agnus castus fruit extract: Prospective, randomised, placebo controlled study. British Medical Journal, 322(7279), 134–137. https://doi.org/10.1136/bmj.322.7279.134
- Berger, D., Schaffner, W., Schrader, E., Meier, B., & Brattström, A. (2000). Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS). Archives of Gynecology and Obstetrics, 264(3), 150–153. https://doi.org/10.1007/s004040000123
- Ma, L., Lin, S., Chen, R., Zhang, Y., Chen, F., & Wang, X. (2010). Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Australian and New Zealand Journal of Obstetrics and Gynaecology, 50(2), 189–193. https://doi.org/10.1111/j.1479-828X.2010.01137.x
- Mehrangiz Zamani, Nosrat Neghab, & Saadat Torabian. (n.d.). Therapeutic effect of Vitex agnus castus in patients with premenstrual syndrome – PubMed. Retrieved April 29, 2021, from https://pubmed.ncbi.nlm.nih.gov/22359078/
- Sorge, R. E., Martin, L. J., Isbester, K. A., Sotocinal, S. G., Rosen, S., Tuttle, A. H., Wieskopf, J. S., Acland, E. L., Dokova, A., Kadoura, B., Leger, P., Mapplebeck, J. C. S., McPhail, M., Delaney, A., Wigerblad, G., Schumann, A. P., Quinn, T., Frasnelli, J., Svensson, C. I., … Mogil, J. S. (2014). Olfactory exposure to males, including men, causes stress and related analgesia in rodents. Nature Methods, 11(6), 629–632. https://doi.org/10.1038/nmeth.2935
- Pandey, U. B., & Nichols, C. D. (2011). Human disease models in drosophila melanogaster and the role of the fly in therapeutic drug discovery. Pharmacological Reviews, 63(2), 411–436. https://doi.org/10.1124/pr.110.003293
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